Featured Research
My completed and ongoing research projects along with publications.
Research Projects
Exploring metabolic interactions, heterogeneity and plasticity in Tumors
Exploring metabolic heterogeneity in tumors through the integration of single-cell RNA sequencing data with genome-scale metabolic model, Department of Bioscience and Biotechnology, IIT Kharagpur.
Genome-scale Metabolic Model of L. ruminis
Reconstruction and analysis of genome-scale metabolic model of Lactobacillus ruminis to explore its function and role in the gut of Indian Type II diabetes patients.
Temozolomide & Magnolol in Glioma Treatment
Studying the combinational effect of Temozolomide and Magnolol in glioma treatment and investigating the molecular mechanism behind its improved response.
Mutation in Malaria Diagnostic Genes
Finding mutation in HRP and LDH genes in Plasmodium vivax and Plasmodium falciparum and their implication on Rapid Diagnostic Test kits for malaria.
Publications
Manuscripts and associated tools from my research.
Single-cell RNA-seq infused population modeling reveals intratumor metabolic heterogeneity and context-dependent metabolic plasticity in pipeline
Pareto-frontal of LUAD reveals stage dependent functional plasticity in pipeline
Increased heterogeneity in expression of genes associated with cancer progression and drug resistance published
Skills
Technical competencies across computation and experimentation.
Research Skills — Computational
Research Skills — Experimental
Conferences
Cold Spring Harbor Laboratory, NY, USA
Poster — Investigating heterogeneity and interaction of cancer metabolism via single-cell RNA sequencing data-infused population metabolic model. Meeting on Biology of Cancer: Microenvironment and Metastasis.
ICTS, TIFR, Bangalore — Mathonco 42
Poster — Capturing intratumor metabolic heterogeneity through integration of single-cell transcriptomic data with genome-scale metabolic models.
BESCON 4 — IIT Kharagpur & Bose Institute, Kolkata
Poster — Exploration of system phenotype by integrating transcriptome with higher order metabolic models.
National Symposium on Omics Applications — IIT Kharagpur
Volunteered and presented orally at the symposium and workshop on Omics Applications for Health and Environment.
Lectures & Workshops
GN Ramachandran Lecture Series on Bioinformatics and Computational Biology — IIT Kharagpur (2022 & 2023).
Human Cell Atlas Asia 2023 Meeting (27–28 November 2023) — attended.